COQ6

Across TCGA pan-cancer cohorts, COQ6 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of COQ6’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where COQ6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types COQ6 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

LUAD, BLCA, and LIHC are the cancer types where COQ6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in COQ6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+0.469	<.001	9	view →
BLCA	All	All	+0.401	<.001	8	view →
LIHC	Female	II,III,IV	+0.529	<.001	7	view →
KICH	Female	All	−0.662	<.001	6	view →
UCEC	All	II,III,IV	+0.445	<.001	6	view →
KIRC	Male	All	−0.387	<.001	6	view →
HNSC	Female	All	+0.345	.017	5	view →
COAD	Male	All	−0.175	.022	3	view →
CHOL	All	II,III,IV	+0.639	.036	2	view →
THCA	Male	IV	−0.356	.015	2	view →
KIRP	Male	All	−0.295	.020	2	view →
PRAD	All	All	+0.188	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

COQ6–LUAD

Open the LUAD breakdown →