COQ6

Across TCGA patient cohorts, COQ6 mutation is significantly associated with the RNA expression of many other genes, with 2,859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COQ6-associated genes across cancer lineages are RNA5SP417, RNA5SP87, and RNA5SP59. Each is linked with COQ6 in more than 2 cancer types. Because this analysis shows association rather than direction, both COQ6-to-partner and partner-to-COQ6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP417 grouped by COQ6-low versus COQ6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ6→partner) and Y-score (partner→COQ6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP417 →	+0.520	+2.029	<.001	.007	3	3
SKCM	RNA5SP87 →	+0.270	+4.743	<.001	.005	3	2
KIRP	RNA5SP59 →	+0.395	+5.376	<.001	.005	3	2
KIRP	UBE2V1P9 →	+0.138	+5.376	<.001	.005	3	2
UCEC	NOLC1P1 →	+0.091	+2.082	<.001	.001	3	2
UCEC	RNA5SP419 →	+0.580	+2.077	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,859 associations by consensus.

RNA5SP417 by COQ6 expression — UCEC

Explore this box plot interactively →