COQ4

Across TCGA patient cohorts, COQ4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,696 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COQ4-associated proteins across cancer lineages are PRRC2B, PTPA, and SEC16A. Each is linked with COQ4 in more than 6 cancer types. Because this analysis shows association rather than direction, both COQ4-to-partner and partner-to-COQ4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ4 versus PRRC2B in LSCC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ4→partner) and Y-score (partner→COQ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRRC2B →	+0.259	+0.288	<.001	<.001	3	7
OV	PTPA →	+0.806	+0.964	<.001	<.001	3	7
BRCA	SEC16A →	+0.252	+0.440	<.001	<.001	3	7
LSCC	WDR5 →	+0.263	+0.349	<.001	<.001	3	6
UCEC	ENDOG →	+0.687	+0.812	<.001	<.001	3	6
CCRCC	HSP90B1 →	-0.405	-0.416	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,696 associations by consensus.

COQ4 vs PRRC2B — LSCC

Explore this scatter interactively →