COQ4

Across TCGA cell cohorts, COQ4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,233 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COQ4-associated GO terms across cancer lineages are CTP salvage, Dolichol phosphate mannose biosynthetic process, and Transcription pausing by RNA polymerase II. Each is linked with COQ4 in more than 16 cancer types. Because this analysis shows association rather than direction, both COQ4-to-partner and partner-to-COQ4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTP salvage grouped by COQ4-low versus COQ4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ4→partner) and Y-score (partner→COQ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CTP salvage →	+0.131	+0.853	<.001	<.001	3	17
STOMACH	Dolichol phosphate mannose biosynthetic process →	+0.117	+0.583	.001	.002	2	16
BONE	Transcription pausing by RNA polymerase II →	+0.164	+0.728	<.001	<.001	3	14
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.100	+0.736	<.001	<.001	3	14
BONE	Nuclear export →	+0.074	+0.809	<.001	<.001	3	13
BONE	Positive regulation of DNA-templated DNA replication →	+0.186	+1.067	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,233 associations by consensus.

CTP salvage by COQ4 expression — URINARY_TRACT

Explore this box plot interactively →