COQ3

Across TCGA cell cohorts, COQ3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,602 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COQ3-associated GO terms across cancer lineages are Ketone biosynthetic process, Quinone biosynthetic process, and Ubiquinone metabolic process. Each is linked with COQ3 in more than 18 cancer types. Because this analysis shows association rather than direction, both COQ3-to-partner and partner-to-COQ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ketone biosynthetic process grouped by COQ3-low versus COQ3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ3→partner) and Y-score (partner→COQ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Ketone biosynthetic process →	+0.098	+0.870	.001	<.001	3	19
OESOPHAGUS	Quinone biosynthetic process →	+0.107	+0.949	.001	.002	3	18
URINARY_TRACT	Ubiquinone metabolic process →	+0.096	+0.833	<.001	<.001	3	18
OESOPHAGUS	Ubiquinone biosynthetic process →	+0.107	+0.949	.001	.002	3	18
BLOOD_Myeloma	Quinone metabolic process →	+0.094	+1.397	<.001	<.001	3	17
BONE	DNA replication initiation →	+0.172	+0.614	.002	.004	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,602 associations by consensus.

Ketone biosynthetic process by COQ3 expression — OVARY

Explore this box plot interactively →