COQ3

Across TCGA cell cohorts, COQ3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible COQ3-associated genes across cancer lineages are KRT77 and NLRP2B. Each is linked with COQ3 in more than 1 cancer types. Because this analysis shows association rather than direction, both COQ3-to-partner and partner-to-COQ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT77 grouped by COQ3-low versus COQ3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ3→partner) and Y-score (partner→COQ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KRT77 →	+0.153	+4.095	<.001	.009	3	1
SKIN	NLRP2B →	+0.011	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KRT77 by COQ3 expression — SKIN

Explore this box plot interactively →