COQ2

Across TCGA patient cohorts, COQ2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,426 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible COQ2-associated proteins across cancer lineages are RRM2, SMC4, and RFC1_T506. Each is linked with COQ2 in more than 6 cancer types. Because this analysis shows association rather than direction, both COQ2-to-partner and partner-to-COQ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ2 versus RRM2 in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ2→partner) and Y-score (partner→COQ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM2 →	+0.774	+0.363	<.001	.008	3	7
BRCA	SMC4 →	+0.541	+0.490	<.001	.001	3	7
PDAC	RFC1_T506 →	+0.843	+0.340	.002	.006	3	6
BRCA	RRM2_S20 →	+1.227	+0.667	<.001	<.001	3	6
BRCA	SMC2 →	+0.517	+0.478	<.001	.001	3	6
LSCC	CHAF1B_S410 →	+0.783	+0.480	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,426 associations by consensus.

COQ2 vs RRM2 — UCEC

Explore this scatter interactively →