COQ2

Across TCGA patient cohorts, COQ2 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COQ2-associated genes across cancer lineages are MIR2392, WBP1LP7, and ZYXP1. Each is linked with COQ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COQ2-to-partner and partner-to-COQ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR2392 grouped by COQ2-low versus COQ2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ2→partner) and Y-score (partner→COQ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR2392 →	+0.268	+7.640	<.001	.009	3	1
BLCA	WBP1LP7 →	+0.069	+7.640	<.001	.009	3	1
BLCA	ZYXP1 →	+0.198	+7.640	<.001	.009	3	1
UCEC	SPDYE9 →	+0.007	+4.242	<.001	.006	3	1
UCEC	SNORD3A →	+0.265	+2.620	.009	.008	3	1
UCEC	CCDC58P3 →	+0.510	+3.573	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

MIR2392 by COQ2 expression — BLCA

Explore this box plot interactively →