COPS7B

Across TCGA cell cohorts, COPS7B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,685 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COPS7B-associated GO terms across cancer lineages are Regulation of microtubule-based process, Chromosome separation, and COP9 signalosome assembly. Each is linked with COPS7B in more than 16 cancer types. Because this analysis shows association rather than direction, both COPS7B-to-partner and partner-to-COPS7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule-based process grouped by COPS7B-low versus COPS7B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS7B→partner) and Y-score (partner→COPS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of microtubule-based process →	+0.052	+0.677	.001	<.001	3	17
BONE	Chromosome separation →	+0.238	+0.794	<.001	<.001	3	17
BREAST	COP9 signalosome assembly →	+0.150	+0.751	<.001	<.001	3	17
BREAST	Regulation of double-strand break repair →	+0.070	+0.809	<.001	.001	3	16
BREAST	Anaphase-promoting complex-dependent catabolic process →	+0.100	+0.714	<.001	<.001	3	16
OVARY	Heterochromatin formation →	+0.072	+0.630	<.001	.005	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,685 associations by consensus.

Regulation of microtubule-based process by COPS7B expression — STOMACH

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