COPS5

Across TCGA patient cohorts, COPS5 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,252 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COPS5-associated proteins across cancer lineages are YTHDF3, VCPIP1, and TCEA1. Each is linked with COPS5 in more than 8 cancer types. Because this analysis shows association rather than direction, both COPS5-to-partner and partner-to-COPS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPS5 versus YTHDF3 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS5→partner) and Y-score (partner→COPS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YTHDF3 →	+0.313	+0.599	<.001	<.001	3	9
BRCA	VCPIP1 →	+0.268	+0.486	<.001	<.001	3	8
COAD	TCEA1 →	+0.380	+0.569	<.001	<.001	3	7
BRCA	SCRIB →	+0.361	+0.402	<.001	.007	2	7
BRCA	ARFGEF1 →	+0.422	+0.497	<.001	<.001	3	6
BRCA	STAU2 →	+0.311	+0.340	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,252 associations by consensus.

COPS5 vs YTHDF3 — BRCA

Explore this scatter interactively →