COPS5

Across TCGA patient cohorts, COPS5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,907 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COPS5-associated genes across cancer lineages are PDCD4, CCL11, and ERICH5. Each is linked with COPS5 in more than 2 cancer types. Because this analysis shows association rather than direction, both COPS5-to-partner and partner-to-COPS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPS5 versus PDCD4 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS5→partner) and Y-score (partner→COPS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDCD4 →	+0.876	+0.165	<.001	<.001	3	3
OV	CCL11 →	-1.907	-0.180	<.001	.009	3	3
OV	ERICH5 →	-1.236	-0.214	<.001	<.001	3	3
UCEC	FAM83D →	-1.045	-0.141	.005	.001	3	3
UCEC	CEP72 →	-0.651	-0.132	.002	.001	3	3
GBM	SPC25 →	-0.715	-0.122	.005	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,907 associations by consensus.

COPS5 vs PDCD4 — BRCA

Explore this scatter interactively →