COPS5

Across TCGA patient cohorts, COPS5 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,158 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COPS5-associated proteins across cancer lineages are COPS4, COPS6, and COPS8. Each is linked with COPS5 in more than 8 cancer types. Because this analysis shows association rather than direction, both COPS5-to-partner and partner-to-COPS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPS5 versus COPS4 in BRCA, with a Pearson correlation of 0.83.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS5→partner) and Y-score (partner→COPS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COPS4 →	+0.261	+0.269	<.001	<.001	3	9
BRCA	COPS6 →	+0.317	+0.281	<.001	<.001	3	9
BRCA	COPS8 →	+0.254	+0.259	<.001	<.001	3	9
BRCA	COPS2 →	+0.255	+0.269	<.001	<.001	3	8
OV	COPS3 →	+0.209	+0.202	<.001	<.001	3	8
BRCA	GPS1 →	+0.206	+0.244	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,158 associations by consensus.

COPS5 vs COPS4 — BRCA

Explore this scatter interactively →