COPG2

Across TCGA cell cohorts, COPG2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COPG2-associated genes across cancer lineages are ACTRT1, AMELX, and SPHKAP. Each is linked with COPG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COPG2-to-partner and partner-to-COPG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTRT1 grouped by COPG2-low versus COPG2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPG2→partner) and Y-score (partner→COPG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ACTRT1 →	+0.028	+5.201	<.001	.006	3	1
BLOOD_Leukemia	AMELX →	+0.038	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SPHKAP →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	SPPL2C →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	HIGD1C →	+0.108	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CBLN4 →	+0.006	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ACTRT1 by COPG2 expression — BLOOD_Leukemia

Explore this box plot interactively →