Across TCGA patient cohorts, COPB2 protein abundance is significantly associated with the RNA expression of many other genes, with 21,446 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COPB2-associated genes across cancer lineages are XBP1, SEC24D, and LAMB2P1. Each is linked with COPB2 in more than 5 cancer types. Because this analysis shows association rather than direction, both COPB2-to-partner and partner-to-COPB2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPB2→partner) and Y-score (partner→COPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	XBP1 →	+1.265	+0.188	.004	.003	3	6
COAD	SEC24D →	+0.505	+0.168	<.001	<.001	3	6
GBM	LAMB2P1 →	-0.774	-0.211	<.001	<.001	3	6
COAD	HDAC5 →	-0.471	-0.145	.009	.008	3	6
LUAD	FKBP11 →	+0.503	+0.183	<.001	<.001	3	6
OV	ZEB1-AS1 →	-0.628	-0.205	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,446 associations by consensus.

Exploration

COPB2 survival (RNA) · tumor vs normal (RNA) · all COPB2 data types