COPB1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COPB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,589 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COPB1-associated proteins across cancer lineages are TSG101, C11orf58, and CDK7. Each is linked with COPB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COPB1-to-partner and partner-to-COPB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPB1 versus TSG101 in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COPB1→partner) and Y-score (partner→COPB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACTSG101 →+0.237+0.259.002.00236
OVC11orf58 →+0.340+0.490<.001<.00136
GBMCDK7 →+0.300+0.276<.001.00136
BRCAPIK3C2A →+0.278+0.545<.001<.00135
HNSCGTF2H1 →+0.256+0.598<.001<.00135
HNSCCDKN1B →-0.371-0.544.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,589 associations by consensus.

COPB1 vs TSG101 — PDAC

Per-sample scatter of COPB1 vs TSG101 in PDAC (Pearson r = 0.41).

Explore this scatter interactively →

Exploration