COPB1

Across TCGA patient cohorts, COPB1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,429 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COPB1-associated genes across cancer lineages are KDELR3, CEP68, and SEC24D. Each is linked with COPB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both COPB1-to-partner and partner-to-COPB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPB1 versus KDELR3 in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPB1→partner) and Y-score (partner→COPB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KDELR3 →	+1.215	+0.209	<.001	<.001	3	7
LSCC	CEP68 →	-0.557	-0.204	<.001	<.001	3	7
COAD	SEC24D →	+0.647	+0.179	.001	<.001	3	7
LSCC	RPS6KA5 →	-0.648	-0.155	<.001	<.001	3	5
GBM	EPX →	-0.298	-0.144	<.001	<.001	3	5
HNSC	RBMX →	-0.854	-0.155	.008	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,429 associations by consensus.

COPB1 vs KDELR3 — BRCA

Explore this scatter interactively →