COP1

Across TCGA patient cohorts, COP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,352 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COP1-associated proteins across cancer lineages are PARP1, GATAD2B, and PRCC. Each is linked with COP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both COP1-to-partner and partner-to-COP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COP1 versus PARP1 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COP1→partner) and Y-score (partner→COP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PARP1 →	+0.449	+0.401	.001	.001	3	8
HNSC	GATAD2B →	+0.316	+0.595	<.001	<.001	3	8
BRCA	PRCC →	+0.357	+0.412	<.001	<.001	3	7
OV	TIPRL →	+0.380	+0.340	.004	.004	3	7
GBM	RPRD2 →	+0.325	+0.433	<.001	<.001	3	7
UCEC	SETDB1 →	+0.331	+0.573	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,352 associations by consensus.

COP1 vs PARP1 — OV

Explore this scatter interactively →