COMMD5

Across TCGA cell cohorts, COMMD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,124 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COMMD5-associated GO terms across cancer lineages are Cellular response to sodium arsenite, Cellular response to salt, and U4 snRNA 3'-end processing. Each is linked with COMMD5 in more than 9 cancer types. Because this analysis shows association rather than direction, both COMMD5-to-partner and partner-to-COMMD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to sodium arsenite grouped by COMMD5-low versus COMMD5-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD5→partner) and Y-score (partner→COMMD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cellular response to sodium arsenite →	+0.101	+0.443	<.001	.001	3	10
LUNG_SCLC	Cellular response to salt →	+0.111	+0.753	.001	<.001	3	9
URINARY_TRACT	U4 snRNA 3'-end processing →	+0.134	+0.836	<.001	<.001	3	8
URINARY_TRACT	Dolichol phosphate mannose biosynthetic process →	+0.093	+0.774	.001	.001	3	8
BLOOD_Leukemia	Central nervous system morphogenesis →	-0.433	-0.642	.003	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Blastocyst growth →	+0.119	+0.703	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,124 associations by consensus.

Cellular response to sodium arsenite by COMMD5 expression — LUNG_SCLC

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