COMMD3-BMI1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, COMMD3-BMI1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible COMMD3-BMI1-associated genes across cancer lineages are OPRPN. Each is linked with COMMD3-BMI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COMMD3-BMI1-to-partner and partner-to-COMMD3-BMI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPRPN grouped by COMMD3-BMI1-low versus COMMD3-BMI1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD3-BMI1→partner) and Y-score (partner→COMMD3-BMI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADOPRPN →+0.040+4.887<.001.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OPRPN by COMMD3-BMI1 expression — LUNG_NSCLC_LUAD

Box plot of OPRPN in COMMD3-BMI1-low vs COMMD3-BMI1-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration