COMMD1

Across TCGA patient cohorts, COMMD1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,512 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COMMD1-associated genes across cancer lineages are AXL, SCAI, and PLA2G15. Each is linked with COMMD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both COMMD1-to-partner and partner-to-COMMD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COMMD1 versus AXL in BRCA, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD1→partner) and Y-score (partner→COMMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AXL →	+0.639	+0.243	<.001	.004	3	5
HNSC	SCAI →	-0.472	-0.153	.005	.008	3	4
CCRCC	PLA2G15 →	+0.556	+0.158	<.001	<.001	3	4
LUAD	ATP6V1B2 →	+0.368	+0.128	<.001	.001	3	4
GBM	TPP1 →	+0.626	+0.163	<.001	<.001	3	4
UCEC	CARD6 →	+0.906	+0.229	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,512 associations by consensus.

COMMD1 vs AXL — BRCA

Explore this scatter interactively →