COMMD1

Across TCGA cell cohorts, COMMD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,414 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COMMD1-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Actin filament fragmentation, and Body fluid secretion. Each is linked with COMMD1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COMMD1-to-partner and partner-to-COMMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by COMMD1-low versus COMMD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD1→partner) and Y-score (partner→COMMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.070	+0.821	<.001	<.001	3	10
LIVER	Actin filament fragmentation →	+0.133	+1.044	<.001	.003	3	9
OESOPHAGUS	Body fluid secretion →	-0.168	-0.979	.003	.002	3	8
BONE	Lactation →	-0.190	-0.843	<.001	<.001	3	8
BLOOD_Myeloma	Regulation of ERAD pathway →	+0.076	+1.007	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Negative regulation of Arp2/3 complex-mediated actin nucleation →	-0.225	-0.679	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,414 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by COMMD1 expression — BONE

Explore this box plot interactively →