COLEC12

Across TCGA cell cohorts, COLEC12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,081 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible COLEC12-associated GO terms across cancer lineages are Regulation of postsynaptic membrane potential, Transcription initiation at RNA polymerase II promoter, and COPII-coated vesicle budding. Each is linked with COLEC12 in more than 8 cancer types. Because this analysis shows association rather than direction, both COLEC12-to-partner and partner-to-COLEC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of postsynaptic membrane potential grouped by COLEC12-low versus COLEC12-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COLEC12→partner) and Y-score (partner→COLEC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of postsynaptic membrane potential →	-0.163	-0.411	<.001	.009	3	9
LUNG_NSCLC_LUSC	Transcription initiation at RNA polymerase II promoter →	+0.076	+0.357	<.001	<.001	3	7
SOFT_TISSUE	COPII-coated vesicle budding →	+0.062	+2.166	.007	.005	3	7
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.100	+0.523	<.001	.007	3	7
PANCREAS	Cytoplasmic translation →	+0.069	+0.019	<.001	<.001	3	7
BONE	Vesicle cargo loading →	+0.107	+2.719	.006	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,081 associations by consensus.

Regulation of postsynaptic membrane potential by COLEC12 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →