COLEC12

Across TCGA cell cohorts, COLEC12 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible COLEC12-associated genes across cancer lineages are MYL10, CROCC2, and SSX7. Each is linked with COLEC12 in more than 1 cancer types. Because this analysis shows association rather than direction, both COLEC12-to-partner and partner-to-COLEC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYL10 grouped by COLEC12-low versus COLEC12-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COLEC12→partner) and Y-score (partner→COLEC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MYL10 →	+0.651	+4.011	<.001	.009	3	1
PANCREAS	CROCC2 →	+0.074	+4.237	<.001	.006	3	1
STOMACH	SSX7 →	+0.325	+4.285	<.001	.007	3	1
STOMACH	CT47A6 →	+0.035	+4.285	<.001	.007	3	1
STOMACH	CT47B1 →	+0.037	+4.129	<.001	.007	3	1
LUNG_SCLC	DHRS7C →	+1.130	+3.523	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

MYL10 by COLEC12 expression — PANCREAS

Explore this box plot interactively →