COLEC11

Across TCGA patient cohorts, COLEC11 mutation is significantly associated with the RNA expression of many other genes, with 1,525 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COLEC11-associated genes across cancer lineages are OIP5, KIAA1191, and UBR7. Each is linked with COLEC11 in more than 2 cancer types. Because this analysis shows association rather than direction, both COLEC11-to-partner and partner-to-COLEC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by COLEC11-low versus COLEC11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COLEC11→partner) and Y-score (partner→COLEC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OIP5 →	+0.684	+2.191	.003	.002	3	3
UCEC	KIAA1191 →	+0.413	+1.776	.003	.008	3	3
UCEC	UBR7 →	+0.577	+3.721	<.001	<.001	3	3
UCEC	NDEL1 →	+0.407	+2.415	.002	.003	3	3
UCEC	DIS3L →	+0.470	+2.662	.001	<.001	3	3
UCEC	GLOD4 →	+0.460	+2.673	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,525 associations by consensus.

OIP5 by COLEC11 expression — UCEC

Explore this box plot interactively →