COLEC11

Across TCGA cell cohorts, COLEC11 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible COLEC11-associated genes across cancer lineages are ACTRT1, WFDC8, and KRTAP1-4. Each is linked with COLEC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both COLEC11-to-partner and partner-to-COLEC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTRT1 grouped by COLEC11-low versus COLEC11-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COLEC11→partner) and Y-score (partner→COLEC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	ACTRT1 →	+0.023	+4.906	<.001	.006	3	1
OESOPHAGUS	WFDC8 →	+0.020	+4.906	<.001	.006	3	1
OESOPHAGUS	KRTAP1-4 →	+0.143	+4.906	<.001	.006	3	1
OVARY	MS4A10 →	+0.013	+5.196	<.001	.005	3	1
LARGE_INTESTINE	CHRNA2 →	+0.095	+3.453	<.001	.009	3	1
LARGE_INTESTINE	TBC1D21 →	+0.010	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ACTRT1 by COLEC11 expression — OESOPHAGUS

Explore this box plot interactively →