Across TCGA patient cohorts, COLCA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,484 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible COLCA2-associated proteins across cancer lineages are ADD3, EPB41L1, and DLG3. Each is linked with COLCA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both COLCA2-to-partner and partner-to-COLCA2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COLCA2→partner) and Y-score (partner→COLCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADD3 →	+0.393	+0.447	<.001	.001	3	6
HNSC	EPB41L1 →	+0.641	+0.761	.001	.001	3	6
UCEC	DLG3 →	+0.432	+1.087	<.001	<.001	3	6
LUAD	SRA1 →	-0.277	-0.599	.001	.004	3	5
PDAC	BZW1 →	-0.355	-0.870	<.001	<.001	3	5
OV	DDAH1 →	+0.533	+0.791	.001	.006	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,484 associations by consensus.

Exploration

COLCA2 survival (RNA) · tumor vs normal (RNA) · all COLCA2 data types