COL8A2

Across TCGA cell cohorts, COL8A2 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible COL8A2-associated genes across cancer lineages are OR2A5, PIP, and LY6L. Each is linked with COL8A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL8A2-to-partner and partner-to-COL8A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2A5 grouped by COL8A2-low versus COL8A2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL8A2→partner) and Y-score (partner→COL8A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR2A5 →	+0.013	+2.974	.003	.006	3	2
STOMACH	PIP →	+0.477	+3.428	<.001	.008	3	1
LUNG_SCLC	LY6L →	+0.231	+4.269	.002	.005	3	1
SKIN	AVPR1B →	+0.013	+5.415	<.001	.004	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.049	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP19-3 →	+0.132	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

OR2A5 by COL8A2 expression — OVARY

Explore this box plot interactively →