COL6A5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COL6A5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,737 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COL6A5-associated genes across cancer lineages are TAF11, PIN4, and TMEM97. Each is linked with COL6A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL6A5-to-partner and partner-to-COL6A5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL6A5 versus TAF11 in LSCC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A5→partner) and Y-score (partner→COL6A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTAF11 →-0.455-0.494<.001<.00133
OVPIN4 →-0.517-0.610.008.00132
LSCCTMEM97 →-0.650-0.289<.001.00132
LSCCTIMM8A →-0.630-0.563<.001<.00132
OVTMEM14B →-0.832-0.611<.001.00132
OVMPLKIP →-0.652-0.860.002.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,737 associations by consensus.

COL6A5 vs TAF11 — LSCC

Per-sample scatter of COL6A5 vs TAF11 in LSCC (Pearson r = -0.29).

Explore this scatter interactively →

Exploration