COL6A2

Across TCGA cell cohorts, COL6A2 mutation is significantly associated with the RNA expression of many other genes, with 418 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL6A2-associated genes across cancer lineages are BHLHA9, LALBA, and TINAG. Each is linked with COL6A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL6A2-to-partner and partner-to-COL6A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BHLHA9 grouped by COL6A2-low versus COL6A2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A2→partner) and Y-score (partner→COL6A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	BHLHA9 →	+0.036	+5.977	<.001	.001	3	2
BLOOD_Myeloma	LALBA →	+0.030	+4.807	<.001	.006	3	2
BREAST	TINAG →	+0.170	+2.819	.006	.006	3	2
BLOOD_Leukemia	CHST9 →	+0.013	+2.387	.002	.007	3	2
SKIN	MINAR2 →	+0.006	+3.240	<.001	.004	3	2
LARGE_INTESTINE	GCH1 →	+0.507	+3.087	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 418 associations by consensus.

BHLHA9 by COL6A2 expression — SOFT_TISSUE

Explore this box plot interactively →