COL6A1

Across TCGA patient cohorts, COL6A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,608 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COL6A1-associated proteins across cancer lineages are ZYX, COL12A1, and COL1A1. Each is linked with COL6A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL6A1-to-partner and partner-to-COL6A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL6A1 versus ZYX in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A1→partner) and Y-score (partner→COL6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZYX →	+0.558	+1.051	<.001	<.001	3	10
OV	COL12A1 →	+1.003	+1.542	<.001	<.001	3	10
HNSC	COL1A1 →	+0.916	+1.114	<.001	<.001	3	10
GBM	COL3A1 →	+1.024	+1.208	<.001	<.001	3	10
BRCA	TIMP2 →	+0.642	+1.046	<.001	<.001	3	10
BRCA	NXN →	+0.725	+1.398	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,608 associations by consensus.

COL6A1 vs ZYX — UCEC

Explore this scatter interactively →