COL6A1

Across TCGA cell cohorts, COL6A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,220 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COL6A1-associated GO terms across cancer lineages are Skeletal muscle fiber development, Maintenance of protein location, and Positive regulation of focal adhesion assembly. Each is linked with COL6A1 in more than 17 cancer types. Because this analysis shows association rather than direction, both COL6A1-to-partner and partner-to-COL6A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skeletal muscle fiber development grouped by COL6A1-low versus COL6A1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A1→partner) and Y-score (partner→COL6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Skeletal muscle fiber development →	+0.232	+3.783	<.001	.001	3	18
LIVER	Maintenance of protein location →	+0.139	+2.974	<.001	<.001	3	16
BONE	Positive regulation of focal adhesion assembly →	+0.209	+3.578	<.001	<.001	3	16
URINARY_TRACT	Myotube cell development →	+0.175	+4.348	<.001	<.001	3	16
LIVER	Maintenance of protein location in cell →	+0.140	+2.974	<.001	<.001	3	16
BONE	Collagen biosynthetic process →	+0.278	+3.707	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,220 associations by consensus.

Skeletal muscle fiber development by COL6A1 expression — LIVER

Explore this box plot interactively →