COL5A3

Across TCGA cell cohorts, COL5A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,650 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible COL5A3-associated GO terms across cancer lineages are Collagen metabolic process, Regulation of transepithelial transport, and Elastic fiber assembly. Each is linked with COL5A3 in more than 6 cancer types. Because this analysis shows association rather than direction, both COL5A3-to-partner and partner-to-COL5A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen metabolic process grouped by COL5A3-low versus COL5A3-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL5A3→partner) and Y-score (partner→COL5A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Collagen metabolic process →	+0.148	+1.529	<.001	<.001	3	7
PANCREAS	Regulation of transepithelial transport →	+0.110	+0.347	<.001	.004	3	7
CNS	Elastic fiber assembly →	+0.281	+1.592	<.001	.001	3	6
BONE	Pyrimidine-containing compound transmembrane transport →	-0.119	-1.467	.003	.003	3	6
SKIN	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.069	+1.774	<.001	.001	3	5
SKIN	Thiamine transport →	-0.697	-1.345	.006	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,650 associations by consensus.

Collagen metabolic process by COL5A3 expression — CNS

Explore this box plot interactively →