Across TCGA cell cohorts, COL4A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,976 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible COL4A6-associated GO terms across cancer lineages are Cell-substrate junction organization, Positive regulation of extrinsic apoptotic signaling pathway, and Cell-substrate adhesion. Each is linked with COL4A6 in more than 7 cancer types. Because this analysis shows association rather than direction, both COL4A6-to-partner and partner-to-COL4A6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A6→partner) and Y-score (partner→COL4A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cell-substrate junction organization →	+0.177	+1.703	<.001	<.001	3	8
PANCREAS	Positive regulation of extrinsic apoptotic signaling pathway →	+0.069	+1.236	.003	.004	3	8
SKIN	Cell-substrate adhesion →	+0.078	+1.045	<.001	.006	3	8
STOMACH	Zygotic determination of anterior/posterior axis, embryo →	+1.740	+1.911	<.001	.002	3	8
STOMACH	Thorax and anterior abdomen determination →	+1.740	+1.911	<.001	.002	3	8
BREAST	Negative regulation of post-translational protein modification →	+0.071	+1.385	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,976 associations by consensus.

Exploration

COL4A6 survival (RNA) · tumor vs normal (RNA) · all COL4A6 data types