COL4A4

Across TCGA patient cohorts, COL4A4 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,033 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COL4A4-associated proteins across cancer lineages are SORBS3, RPS3A, and HAAO. Each is linked with COL4A4 in more than 6 cancer types. Because this analysis shows association rather than direction, both COL4A4-to-partner and partner-to-COL4A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL4A4 versus SORBS3 in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A4→partner) and Y-score (partner→COL4A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SORBS3 →	+0.494	+0.763	<.001	.007	3	7
LUAD	RPS3A →	-0.218	-1.119	<.001	<.001	3	6
HNSC	HAAO →	+0.530	+1.054	<.001	<.001	3	6
UCEC	HMGN4 →	+0.784	+0.890	<.001	<.001	3	6
UCEC	MECP2 →	+0.485	+0.963	<.001	<.001	3	6
UCEC	ARHGAP31 →	+0.420	+1.040	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,033 associations by consensus.

COL4A4 vs SORBS3 — UCEC

Explore this scatter interactively →