COL4A3

Across TCGA patient cohorts, COL4A3 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,895 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COL4A3-associated proteins across cancer lineages are DNPEP, HMGN4, and MECP2. Each is linked with COL4A3 in more than 6 cancer types. Because this analysis shows association rather than direction, both COL4A3-to-partner and partner-to-COL4A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL4A3 versus DNPEP in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A3→partner) and Y-score (partner→COL4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DNPEP →	+0.271	+1.104	<.001	<.001	3	7
HNSC	HMGN4 →	+0.557	+0.649	<.001	<.001	3	7
PDAC	MECP2 →	+0.461	+0.905	<.001	<.001	3	7
CCRCC	PURA →	+0.297	+1.067	<.001	<.001	3	7
PDAC	OGN →	+0.997	+0.591	<.001	<.001	3	6
LSCC	SEPTIN4_S117 →	+0.813	+0.954	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,895 associations by consensus.

COL4A3 vs DNPEP — LSCC

Explore this scatter interactively →