COL4A3

Across TCGA patient cohorts, COL4A3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,312 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COL4A3-associated genes across cancer lineages are DIPK2B, HELLS, and MMP19. Each is linked with COL4A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both COL4A3-to-partner and partner-to-COL4A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL4A3 versus DIPK2B in BRCA, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A3→partner) and Y-score (partner→COL4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DIPK2B →	+0.639	+0.567	.002	.001	3	4
HNSC	HELLS →	-0.739	-0.609	<.001	.004	3	3
COAD	MMP19 →	+0.929	+0.548	.004	.004	3	3
LUAD	F2RL3 →	+0.717	+0.434	<.001	<.001	3	3
LSCC	STARD8 →	+0.543	+0.333	<.001	<.001	3	3
COAD	GYPC →	+0.736	+0.525	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,312 associations by consensus.

COL4A3 vs DIPK2B — BRCA

Explore this scatter interactively →