COL4A3

Across TCGA cell cohorts, COL4A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,926 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible COL4A3-associated GO terms across cancer lineages are Glomerular basement membrane development, Regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with COL4A3 in more than 8 cancer types. Because this analysis shows association rather than direction, both COL4A3-to-partner and partner-to-COL4A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glomerular basement membrane development grouped by COL4A3-low versus COL4A3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A3→partner) and Y-score (partner→COL4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Glomerular basement membrane development →	-0.295	-1.206	<.001	<.001	3	9
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.069	+1.027	.001	.004	3	7
SKIN	Negative regulation of myoblast fusion →	+0.067	+0.686	<.001	.003	3	7
KIDNEY	Positive regulation of cellular respiration →	+0.147	+1.326	.008	.001	3	6
OVARY	Protein exit from endoplasmic reticulum →	+0.111	+1.634	<.001	.001	3	6
LIVER	Regulation of organelle assembly →	+0.037	+0.795	.007	.004	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,926 associations by consensus.

Glomerular basement membrane development by COL4A3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →