COL4A2-AS1

Across TCGA pan-cancer cohorts, COL4A2-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated COL4A2-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher COL4A2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated COL4A2-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and THCA show a favorable association.

MESO, UVM, and ACC are the cancer types where COL4A2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.398	0.674	<.001	96	view →
UVM	DFS	Quartile	All	0.396	0.841	<.001	71	view →
ACC	DFS	Quartile	All	0.125	0.562	<.001	67	view →
LGG	DFS	Median	All	0.776	0.883	<.001	51	view →
CHOL	OS	Quartile	All	0.439	0.920	.002	46	view →
STAD	DFS	Tertile	All	0.414	0.587	.004	31	view →
HNSC	OS	Tertile	IV	0.532	0.804	.004	30	view →
BRCA	OS	Median	All	0.977	0.948	.013	16	view →
THCA	DFS	Quartile	All	0.922	0.763	.006	14	view →
UCS	DFS	Tertile	IV	0.832	0.364	.024	12	view →
KIRC	DFS	Median	All	0.484	0.679	.016	10	view →
COAD	DFS	Tertile	IV	0.251	0.595	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

COL4A2-AS1–MESO (OS)

Open the MESO breakdown →