COL2A1

Across TCGA patient cohorts, COL2A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,069 significant associations in total. OV shows the largest number of these associations.

The most reproducible COL2A1-associated GO terms across cancer lineages are RNA localization, Transcription elongation-coupled chromatin remodeling, and Kidney epithelium development. Each is linked with COL2A1 in more than 19 cancer types. Because this analysis shows association rather than direction, both COL2A1-to-partner and partner-to-COL2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by COL2A1-low versus COL2A1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL2A1→partner) and Y-score (partner→COL2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA localization →	+0.077	+0.740	<.001	<.001	3	20
STAD	Transcription elongation-coupled chromatin remodeling →	+0.061	+0.803	<.001	<.001	3	20
TGCT	Kidney epithelium development →	+0.062	+3.996	<.001	<.001	3	19
TGCT	Mesonephros development →	+0.068	+4.006	<.001	<.001	3	19
ESCA	Body morphogenesis →	+0.072	+0.714	<.001	<.001	3	18
TGCT	Appendage morphogenesis →	+0.064	+3.692	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,069 associations by consensus.

RNA localization by COL2A1 expression — STAD

Explore this box plot interactively →