Across TCGA patient cohorts, COL25A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,956 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible COL25A1-associated proteins across cancer lineages are LAMC1, PALM2AKAP2, and NID2. Each is linked with COL25A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL25A1-to-partner and partner-to-COL25A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL25A1→partner) and Y-score (partner→COL25A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LAMC1 →	+0.577	+1.409	<.001	<.001	3	6
UCEC	PALM2AKAP2 →	+0.507	+1.179	<.001	<.001	3	6
HNSC	NID2 →	+0.529	+0.596	<.001	<.001	3	5
CCRCC	PRKG1 →	+0.537	+1.299	<.001	<.001	3	5
BRCA	RBMS3 →	+0.390	+0.350	<.001	<.001	3	5
HNSC	VCAN →	+0.964	+0.440	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,956 associations by consensus.

Exploration

COL25A1 survival (RNA) · tumor vs normal (RNA) · all COL25A1 data types