COL21A1

Across TCGA patient cohorts, COL21A1 RNA expression is significantly associated with the RNA expression of many other genes, with 16,599 significant associations in total. THYM shows the largest number of these associations.

The most reproducible COL21A1-associated genes across cancer lineages are SYNPO2, COL14A1, and ARHGEF15. Each is linked with COL21A1 in more than 31 cancer types. Because this analysis shows association rather than direction, both COL21A1-to-partner and partner-to-COL21A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL21A1 versus SYNPO2 in STAD, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL21A1→partner) and Y-score (partner→COL21A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	SYNPO2 →	+2.081	+0.640	<.001	<.001	3	32
ACC	COL14A1 →	+2.756	+1.150	<.001	<.001	3	31
KIRC	ARHGEF15 →	+1.229	+1.360	<.001	<.001	3	31
KIRC	ADGRL4 →	+1.409	+1.436	<.001	<.001	3	30
TGCT	RHOJ →	+1.464	+1.922	<.001	<.001	3	30
TGCT	FAT4 →	+1.513	+1.991	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,599 associations by consensus.

COL21A1 vs SYNPO2 — STAD

Explore this scatter interactively →