COL1A2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COL1A2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,094 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COL1A2-associated genes across cancer lineages are FNDC1, CRISPLD2, and PCOLCE. Each is linked with COL1A2 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL1A2-to-partner and partner-to-COL1A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL1A2 versus FNDC1 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL1A2→partner) and Y-score (partner→COL1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVFNDC1 →+1.581+0.764<.001<.001310
BRCACRISPLD2 →+1.436+0.873<.001<.00139
OVPCOLCE →+1.257+0.731<.001<.00139
OVACTA2 →+1.843+0.747<.001<.00139
GBMCOL1A1 →+2.311+1.180<.001<.00139
BRCALAMA4 →+1.240+0.940<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,094 associations by consensus.

COL1A2 vs FNDC1 — OV

Per-sample scatter of COL1A2 vs FNDC1 in OV (Pearson r = 0.39).

Explore this scatter interactively →

Exploration