COL1A2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, COL1A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,975 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COL1A2-associated GO terms across cancer lineages are Protein folding, Regulation of intracellular transport, and Endocytic recycling. Each is linked with COL1A2 in more than 8 cancer types. Because this analysis shows association rather than direction, both COL1A2-to-partner and partner-to-COL1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by COL1A2-low versus COL1A2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL1A2→partner) and Y-score (partner→COL1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTProtein folding →+0.054+3.086<.001<.00139
BONERegulation of intracellular transport →+0.078+7.139<.001<.00139
BONEEndocytic recycling →+0.084+6.197<.001.00139
BONERegulation of mesenchymal stem cell proliferation →+0.296+6.823<.001<.00139
BONEPositive regulation of mesenchymal stem cell proliferation →+0.296+6.823<.001<.00139
SKINProtein stabilization →+0.049+4.392<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,975 associations by consensus.

Protein folding by COL1A2 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Protein folding in COL1A2-low vs COL1A2-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration