COL17A1

Across TCGA patient cohorts, COL17A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,824 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible COL17A1-associated proteins across cancer lineages are COL17A1_S174, COL17A1_S85, and PLEC. Each is linked with COL17A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both COL17A1-to-partner and partner-to-COL17A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL17A1 versus COL17A1_S174 in LSCC, with a Pearson correlation of 0.88.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL17A1→partner) and Y-score (partner→COL17A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	COL17A1_S174 →	+2.744	+3.108	<.001	<.001	3	7
LSCC	COL17A1_S85 →	+0.895	+1.867	<.001	<.001	3	7
PDAC	PLEC →	+0.453	+1.653	<.001	<.001	3	6
LSCC	PPP1R13L →	+0.539	+1.634	<.001	.001	3	6
PDAC	SLK →	+0.279	+1.811	<.001	<.001	3	6
HNSC	ANXA2 →	+0.434	+1.622	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,824 associations by consensus.

COL17A1 vs COL17A1_S174 — LSCC

Explore this scatter interactively →