COL17A1

Across TCGA patient cohorts, COL17A1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,299 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible COL17A1-associated genes across cancer lineages are SEMA3C, CAV2, and EREG. Each is linked with COL17A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL17A1-to-partner and partner-to-COL17A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL17A1 versus SEMA3C in UCEC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL17A1→partner) and Y-score (partner→COL17A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEMA3C →	+1.874	+2.134	<.001	<.001	3	6
BRCA	CAV2 →	+1.196	+1.558	<.001	<.001	3	5
LUAD	EREG →	+2.040	+1.129	<.001	<.001	3	5
BRCA	MYOF →	+1.101	+1.210	<.001	<.001	3	5
UCEC	ITGA2 →	+1.738	+1.528	.005	.008	3	5
LSCC	AHNAK2 →	+1.259	+1.044	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,299 associations by consensus.

COL17A1 vs SEMA3C — UCEC

Explore this scatter interactively →