COL17A1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, COL17A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,724 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL17A1-associated GO terms across cancer lineages are Mesoderm formation, Hemidesmosome assembly, and Regulation of positive chemotaxis. Each is linked with COL17A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL17A1-to-partner and partner-to-COL17A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesoderm formation grouped by COL17A1-low versus COL17A1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL17A1→partner) and Y-score (partner→COL17A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERMesoderm formation →+0.166+1.496.002.001310
OESOPHAGUSHemidesmosome assembly →+0.264+3.280.003.001210
LUNG_NSCLC_LUSCRegulation of positive chemotaxis →+0.293+3.387<.001.00139
LUNG_SCLCMammary gland morphogenesis →+0.274+1.810<.001.00239
BREASTRegulation of ribonuclease activity →+0.279+2.934<.001<.00139
STOMACHPositive regulation of extracellular exosome assembly →+0.192+3.314.001.00839
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,724 associations by consensus.

Mesoderm formation by COL17A1 expression — LIVER

Box plot of Mesoderm formation in COL17A1-low vs COL17A1-high samples in LIVER.

Explore this box plot interactively →

Exploration