Across TCGA pan-cancer cohorts, COL11A2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated COL11A2 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher COL11A2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated COL11A2 expression acts as an unfavorable survival marker.

LSCC and GBM are the cancer types where COL11A2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	All	0.158	0.789	.022	4	view →
GBM	OS	Median	All	0.242	0.694	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: COL11A2 tumor-vs-normal RNA expression · all COL11A2 data types