Across TCGA cell cohorts, COL11A2 mutation is significantly associated with the RNA expression of many other genes, with 663 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL11A2-associated genes across cancer lineages are LINC02693, SLC25A11, and CCND3. Each is linked with COL11A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL11A2-to-partner and partner-to-COL11A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL11A2→partner) and Y-score (partner→COL11A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LINC02693 →	+0.816	+2.265	<.001	.001	3	3
SKIN	SLC25A11 →	+0.499	+3.234	.009	.004	3	2
SKIN	CCND3 →	+0.756	+2.502	.001	.005	3	2
LARGE_INTESTINE	MXI1 →	+1.052	+2.265	<.001	.001	3	2
SKIN	CLPP →	+0.585	+3.067	.004	.009	3	2
SKIN	OSGIN1 →	+1.110	+3.067	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 663 associations by consensus.

Exploration

COL11A2 survival (RNA) · tumor vs normal (RNA) · all COL11A2 data types