COL11A1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COL11A1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,033 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible COL11A1-associated genes across cancer lineages are GLT8D2, INHBA, and RUNX2. Each is linked with COL11A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both COL11A1-to-partner and partner-to-COL11A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL11A1 versus GLT8D2 in OV, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL11A1→partner) and Y-score (partner→COL11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVGLT8D2 →+1.430+1.326<.001<.00138
OVINHBA →+2.583+1.436<.001<.00138
OVRUNX2 →+1.310+1.218<.001<.00138
OVRCN3 →+1.638+1.549<.001<.00138
OVCOL8A1 →+2.504+1.383<.001<.00138
OVSFRP2 →+4.167+1.435<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,033 associations by consensus.

COL11A1 vs GLT8D2 — OV

Per-sample scatter of COL11A1 vs GLT8D2 in OV (Pearson r = 0.72).

Explore this scatter interactively →

Exploration