COL11A1

Across TCGA patient cohorts, COL11A1 mutation is significantly associated with the RNA expression of many other genes, with 9,803 significant associations in total. STAD shows the largest number of these associations.

The most reproducible COL11A1-associated genes across cancer lineages are OIP5, BCCIP, and CDC20. Each is linked with COL11A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both COL11A1-to-partner and partner-to-COL11A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by COL11A1-low versus COL11A1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL11A1→partner) and Y-score (partner→COL11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	OIP5 →	+0.629	+2.535	<.001	<.001	3	7
STAD	BCCIP →	+0.364	+2.485	<.001	<.001	3	7
LUAD	CDC20 →	+0.640	+1.197	<.001	<.001	3	7
STAD	AUNIP →	+0.575	+2.465	<.001	.001	3	7
STAD	KNSTRN →	+0.499	+2.182	<.001	.001	3	7
STAD	CCNB1 →	+0.789	+2.857	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,803 associations by consensus.

OIP5 by COL11A1 expression — STAD

Explore this box plot interactively →